"It's trial and error," says Jenny Murase, MD, assistant clinical professor at the University of California, San Francisco."We're just testing it to see how [the psoriasis] responds." Your doctor may have to mix different treatments to improve your skin."For a treatment to be working, it has to work to the satisfaction of the patient," says Mark Lebwohl, MD.
The first treatment you try may not be the solution.Psoriasis is generally considered an autoimmune and genetic disease.The endocannabinoid system plays a role in regulating skin cells' life.Speaking March 1 at the 68th Annual Meeting of the American Academy of Dermatology (Academy), dermatologist Alan Menter, MD, FAAD, chair of the Psoriasis Research Unit at Baylor Research Institute in Dallas, addressed the need for psoriasis to be viewed as a serious disease affecting the whole body with significant quality of life issues."In the past, psoriasis was viewed primarily as a cosmetic nuisance that was not thought to extend beyond the obvious plaques apparent on the skin," said Dr. "With the discovery of multiple genes related to psoriasis, a better understanding of the immune system responses involved in this disease, and the frequent associations with other serious diseases, we know that psoriasis is a much more complex disease that demands continual monitoring and evaluation by a dermatologist and, if necessary, other medical professionals to address related health issues." Link between Psoriasis and Other Serious Medical Conditions Over the years, multiple studies have found that psoriasis is associated with a number of potentially serious medical conditions, including cardiovascular disease, cancer and lymphoma, obesity and metabolic syndrome (also known as "Syndrome X"), autoimmune diseases (Crohn's disease and diabetes mellitus I and II, for example), psychiatric diseases (such as depression and sexual dysfunction), psoriatic arthritis, sleep apnea, personal behavior issues, chronic obstructive pulmonary disease (COPD) and even increased mortality. Menter explained that the majority of these diseases can have a significant impact on a patient's overall health and affect psoriasis patients in different degrees of severity.